急性脑血管病与心肌酶谱改变相关性分析

目的探讨急性脑血管病与心肌酶谱改变相关性.方法对206例急性脑血管患者的以下情况进行回顾性调查:血清心肌酶谱,性别,年龄,神志,偏瘫等级,既往有无冠心病史,中医病理因素风、火、痰、瘀、虚,脑出血,脑梗塞,心电图改变,有无脑水肿、肺部感染、消化道出血等严重并发症,预后;并将调研资料经数量化处理输入计算机,应用统计学处理软件SPSS 11.0,进行急性脑血管病诸因素与血清心肌酶谱异常的相关性分析.结果急性脑血管病患者血清心肌酶升高与脑出血呈正相关(r=0.185,P<0.05),与中医病理因素火热呈正相关(r=0.215,P<0.05),与意识障碍呈显著性正相关(r=0.256,P<0.001),与并发症的发生呈显著性正相关(r=0.251,P<0.001),与死亡呈显著性正相关(r=0.312,P<0.001),与中医病理因素风呈负相关(r=-0.139,P<0.05),与中医病理因素瘀呈负相关(r=-0.174,P<0.05),与年龄、偏瘫等级、既往有无冠心病史及中医病理因素痰、虚以及脑梗塞、心电图改变无相关.结论急性脑血管病尤其脑出血伴意识障碍患者血清心肌酶谱容易升高且预后较差.

Correlation between acute cerebrovascular disease and change of myocardia enzymogram

Objective To discuss the correlation between acute cerebrovascular disease (ACD) and change of myocardia enzymogram (ME). Methods The retrospective investigation was made in 206 cases of ACD, which included ME, sex, age, consciousness, degree of paralysis, previous history of coronary heart disease (CHD), pathogenic factors of Chinese medicine (wind, fire, phlegm, stagnation and deficiency), cerebral hemorrhage, cerebral infarction, change of electrocardiogram (ECG), cerebral edema, infection in the lung, hemorrhage of digestive tract, and so on. Then above materials were put into the computer after digital treatment and the correlation between the change of ME and other factors analysed with SPSS 11.0 software. Results The increase of the change of ME in the patients with ACD was correlated to cerebral hemorrhage (r=0.185, P<0.05), and to fire, one of the factors of Chinese medicine (r=0.215, P<0.05). It was correlated significantly to disturbance of consciousness (r=0.256, P<0.001), to occurrence of complications (r=0.251, P<0.001), to death (r=0.312, P<0.001). It was correlated to wind(r=0.139),and negative correlated to stagnation (r=-0.174).It was not correlated to age, degree of paralysis, previous history of CHD and other factors of Chinese medicine (phlegm and deficiency), cerebral infarction and change of ECG. Conclusion The patients with ACD, especially cerebral hemorrhage complicated disturbance of consciousness have an increase tends in change of ME and poor prognosis.