涎腺癌84例临床病理分析

目的探讨84例涎腺癌的病理组织学特点，临床诊断指标及预后分析。方法应用HE染色免疫组织化学观察涎腺癌的特点，采用随访方式追踪观察其预后。结果84例涎腺癌平均年龄为43岁，原发瘤68例，复发瘤16例，多发生于腮腺及腭腺，主要病理类型有恶性多形性腺瘤、粘液表皮样癌、腺样囊性癌、肌上皮癌、皮脂腺癌等，手术治疗后配合化疗，复发率为8％，其1a、3a、5a生存率分别为85％、70％和45％。结论涎腺癌是口颌面部常见恶性肿瘤，临床组织病理学分型很多，且各具有临床病理特征，其预后与病理类型、发生部位、分化程度等有关。

Clinical Pathological Analysis on 84 Cases of Salivary Gland Carcinoma

Objective To investigate the histopathological charateristics, clinical diagnosis criteria and prognosis of salivary gland carcinoma. Methods HE staining and immunohistochemistrical method were employed to observe the feature of the salivary gland carcinoma, and its prognosis was observed at a follow-up. Results Of all 84 cases of salivary gland carcinoma with a mean age of 43 years, 68 were primary tumors and the other 16 were recurrent. The parotid and palatine glands were predilection sites. The major pathological types included malignant pleomorphic adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, myoepithelial carcinoma and sebaceous gland carcinoma. The relapse rate was 8% after postoperative chemotherapy. The 1-, 3- and 5-year survivals were 85, 70, and 45%, respectively. Conclusion Salivary glanct carcinoma is the commonly seen oral and maxillofacial malignant tumor, with many clincally histopathological typing and each with clinically pathological features. The prognosis of the disease is related to pathological type, affecting site and differentiation.