心脏手术对乙肝及乙肝病毒携带者肝功能的影响

目的观察体外循环心脏手术对乙肝（HB）及乙肝病毒（HBV）携带者肝功能的影响。方法对心脏病手术患者于手术前后进行了肝功能测定，其中肝功能正常组45例、HBV携带组42例，HB组18例。结果体外循环对HBV携带者的肝功能无显著影响（P〈0．05），对其术后出血也无明显影响。HB患者体外循环术后谷丙转氨酶（ALT）及谷草转氨酶（AST）显著升高，且其术后出血量较肝功正常者明显增加（P〈0．05）。结论术前肝功能正常的乙肝病毒携带者接受心脏手术是安全的．HB患者心脏手术中肝功能损害是可逆性的，只要采取必要的保护措施也可以接受手术治疗．

The effect of cardiac operation on liver function of hepatitis B(HB)patients and hepatitis B virus(HBV)carriers.

Objective To observe the effect of cardiopulmonary bypass on liver function of hepatitis B(HB) patients and hepatitis B virus(HBV) carriers. Methods The liver function index of 42 hepatitis B virus(HBV) carriers and 14 hepatitis B(HB) patients were determined before and after cardiac operation.They were compared with the liver function index of 45 normal patients concomitantly. Results The levels of ALT and AST were higher in hepatitis group than those in normal and HBV group(P<0.05) and their blood effusion volume post-operative increased significantly in hepatitis group(P<0.05). Conclusion Cardiac operation can be done safely on HBV carriers with normal liver function before operation.as liver function damage among cardiopulmonary bypass is recoverable,The HB patients can accept cardiac operation in case protective necessary measures are taken.