肝病患者血清促红细胞生成素含量分析及意义

探讨不同肝病患者血清EPO含量及病理生理意义。采用放免非平衡法检测 5 0例健康人和不同肝病患者血清EPO含量 ,并进行统计学处理。 18例肝硬化 (其中代偿期 8例 ,失代偿期 10例 )和 11例肝癌患者血清EPO含量明显高于正常对照组 ,P <0 0 0 1;失代偿期明显高于代偿期 ,P <0 0 1。肝硬化与肝癌相比亦有显著性差异 ,P <0 0 0 1。 2 5例急、慢性肝炎与正常对照组无显著性差异 ,P >0 0 5。检测血清EPO含量可为不同肝脏疾病的病理生理进一步研究提供参考

The analysis and significance of EPO in liverish patient serum

To explore the pathophysiologic significance of EPO concentration in various liverish patient's serum. The EPO concentration of 50 normal persons and 53 various liverish patients were detected by using non-balance radio immune assay, and the results were analysed with statistic method. The EPO concentrations of 18 cirrhosis patients (8 cases in compensatory phase; 10 cases in non-compensatory phase) were remarkably higher than thase, of normal control (P<0 001); There were remarkable difference between cirrhosis group and liver cancer group (P<0 001); the EPO concentrations of cirrhosis patients during non-compensatory phase were remarkably higher than those of the patients during compensatory phase, and there were no remarkable difference between acute and chronic hepatitis group and normal control group (P>0 05) The detection of EPO concentration can provide reference to various liverish pathophysiologic research further.