175例子宫内膜异位症药物治疗临床观察

目的 探讨孕三烯酮、口服避孕药敏定偶、中药丹莪妇康煎膏治疗内异症的疗效和安全性差异,指导临床用药.方法 从本院妇科患者中选取有子宫内膜异位症典型症状的患者,回顾分析了175例子宫内膜异位症患者的药物治疗随访资料,比较疗效及副作用发生率.结果 3组药物疗效无明显差异(P＞0.05),孕三烯酮引起的闭经、体重增加、潮热、多毛、痤疮发生率高于敏定偶和丹莪妇康煎膏(P＜0.05).丹莪妇康煎膏引起的肝功能损害仅占1.47%.结论 3种药物治疗内异症疗效无明显差异,敏定偶耐受性好,更容易被患者接受,对肝病患者丹莪妇康煎膏应为首选.

Clinical observation of 175 cases on the effects of medical treatment for endometriosis

OBJECTIVE To investigate the effects and safety of gestrinone,oral contraceptive and traditional Chinese medicine for treating patients with endometriosis.METHODS 175 endometriosis cases were analyzed retrospectively.Of these cases,55 were administered gestrinone,52 were administered oral contraceptive,68 were administered traditional Chinese medicine,curative effects and side effects were compared among these groups.RESULTS There were no significant difference in curative effects among three groups(P>0.05).The side effects rate of gestrinone was significant higher than that of oral contraceptive and traditional Chinese medicine(P<0.05);the incidence rate of hepatic function lesion was significant lower in traditional Chinese medicine group(P<0.05).CONCLUSION There are no difference in curative effect among gestrinone,oral contraceptive and traditional Chinese medicine.Oral contraceptive has a good tolerance and easier to be accept.Traditional Chinese medicine is the first selection for endometriosis with hepatic function lesion.