新诊断2型糖尿病患者周围神经病变临床分析

目的:探讨新诊断2型糖尿病(T2DM)患者周围神经病变相关临床危险因素。方法:随机选择172例新诊断T2DM,经过神经传导速度测定分为神经病变(DPN)组和非DPN组,比较两组临床参数血糖、血压、血脂等,数据经统计学处理。结果:共检出DPN患者49例,DPN患病率为28.4%,DPN组的年龄、收缩压和HbA1c均显著高于非DPN组,差异具有统计学意义(P<0.05),其余各项指标两组间差异均无统计学意义,经Logistic分析HbA1c是DPN的危险因素。结论:新诊断T2DM神经病变发生率较高,HbA1c是DPN的危险因素。

Peripheral Neuropathy in Type 2 Diabetes Newly Diagnosed

Objective:To investigate the clinical risk factors in type 2 diabetic newly diagnosed with peripheral neuropathy.Methods:172 diabetics newly diagnosed were selected randomly.They were divided into peripheral neuropathy group(DPN)and no peripheral neuropathy group(non-DPN)according to the nerve conduction velocity(NCV).Clinical characteristics,including blood pressure,fasting and postprandial blood glucose,HbA1c,lipid profiles,uric acid,insulin and urinary albumin(uAlb) were determined.Data was evaluated using analysis of SPSS11.0.Results:49 diabetics were screened.The DPN group showed older age(58.6±8.3 vs 50.9±5.2,yrs),higher systolic blood pressure(139.3±20.0 vs 128.8±10.2,mmHg)and higher HbA1c(9.8±2.5 vs 7.9±2.3,%),P<0.05.Logistic analysis screened that HbA1c was the independent risk factors for DPN(P<0.05).Conclusion:DPN had higher incidence in T2DM newly diagnosed.Hyperglycemia was important risk factors.