Molecular cloning of monkey histamine H4 receptor |
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| Authors: | Oda Tamaki Matsumoto Shun-ichiro Matsumoto Mitsuyuki Takasaki Jun Kamohara Masazumi Soga Takatoshi Hiyama Hideki Kobori Masato Katoh Masao |
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| Affiliation: | Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd., Ibaraki, Japan. |
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| Abstract: | ![]()
Histamine H(4) receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H(4) receptor was identified. Monkey H(4) receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H(4) receptor will contribute to a better interpretation of effective drug discovery. |
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