Effect of DDAVP on plasma level of factor XII |
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| Authors: | G G Nenci M Berrettini M De Cunto G Agnelli |
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| Institution: | Institutes of Semeiotica Medica;Clinica Medica, University of Perugia Medical School, Perugia, Italy |
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| Abstract: | The effect of DDAVP on blood coagulation factors was investigated after its intravenous infusion into normal subjects. A marked increase in factor XII was observed in addition to the expected rise of factor VIII coagulant activity (VIII:C), factor VIII related antigen (VIIIR:Ag) and plasminogen activator, DDAVP also produced a concomitant but less pronounced rise of factor VII, but there was no change in factors V, IX, X and XI. |
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