| 降血脂药物临床合理用药研究进展 |
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| 引用本文： | 衣淑华,衣淑珍. 降血脂药物临床合理用药研究进展[J]. 国际药学研究杂志, 2012, 39(3): 210-214. DOI: 10.3969/j.issn.1674-0440.2012.03.006 |
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| 作者姓名： | 衣淑华 衣淑珍 |
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| 作者单位： | 1.山东省栖霞市人民医院心内科,栖霞,265300;2.海军总医院药剂科,北京,100048 |
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| 摘 要： | 脂质异常是导致动脉粥样硬化的危险因素之一,对其进行调节和治疗是心血管疾病初级预防和二级预防的基础.除通过饮食调节以外,目前临床常用的治疗策略是服用降血脂药物,如他汀类、贝特类、胆固醇吸收抑制剂、烟酸、胆酸螯合剂和Ω-3脂肪酸等.这些药物作用机制不同但通常互相补充,通过合理搭配使用,可使脂质代谢异常得到纠正.本文对现有凋脂药物的调脂效果和临床合理用药的研究进展进行综述.
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| 关 键 词： | 血脂异常 降血脂药 合理用药 药物不良反应 |
Clinical rational use of lipid-lowering drugs: research advances |
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| YI Shu-hua , YI Shu-zhen. Clinical rational use of lipid-lowering drugs: research advances[J]. Foreign Medical Sciences(Section of Pharmarcy), 2012, 39(3): 210-214. DOI: 10.3969/j.issn.1674-0440.2012.03.006 |
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| Authors: | YI Shu-hua YI Shu-zhen |
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| Affiliation: | 1.Department of Cardiology,Qixia City People′s Hospital,Qixia 265300,China; 2.Department of Pharmacy,General Navy Hospital,Beijing 100048,China) |
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| Abstract: | Dyslipidemia is recognized as a risk factor for cardiovascular diseases.Adjustment and treatment of dyslipidemia is the foundation for both primary and secondary prevention of cardiovascular diseases.Besides being put on a diet,patients should take some medicines,such as statins,fibrates,bile acid sequestrants,niacin,omega-3 and so on that impact on lipid metabolism through a variety of mechanisms.This review provides an overview on how to use lipid-lowering drugs rationally when attempting to normalize serum lipid profiles and reduce risks for cardiovascular diseases and occurring of adverse drug reactions. |
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| Keywords: | dyslipidemia antilipemic agents drug rational use adverse drug reaction |
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