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早产儿甲状腺功能影响因素分析
引用本文:朱艳可,陈泗虎,王楸,池美珠,钱燕. 早产儿甲状腺功能影响因素分析[J]. 中国优生与遗传杂志, 2011, 0(4): 78-79,3
作者姓名:朱艳可  陈泗虎  王楸  池美珠  钱燕
作者单位:温州医学院附属第一医院新生儿科;温州医学院附属第二医院;
摘    要:
目的研究早产儿甲状腺功能三碘甲状腺原氨酸(triiodothyronine,T3)、甲状腺素(thyroxine,T4)、促甲状腺激素(thyroid stimulating hormone,TSH)的影响因素。方法对353例早产儿生后第14天的甲状腺功能进行检测,并收集可能相关的14种因素,运用多元线性回归分析T3、T4、TSH的影响因素。结果在分析的14种因素中对早产儿生后第14天T3有影响的有胎龄、呼吸窘迫综合征(respiratory distress syndrome,RDS)、糖耐量异常,对T4有影响的有胎龄、性别,对TSH有影响的有出生体重比例、性别。结论早产是早产儿暂时性低甲状腺素血症(transient hypothyroxinemia of preterm infant,THOP)的根本原因。胎龄越小,早产儿甲状腺功能越低下。母糖耐量异常、性别、出生体重比值、呼吸窘迫综合征可能影响早产儿的甲状腺功能。

关 键 词:早产儿  甲状腺功能  胎龄  出生体重  暂时性低甲状腺素血症

An analysis of associated factors of thyroid hormones of prematurity
ZHU Yan-ke,CHEN Si-hu,WANG Qiu,CHI Mei-zhu,QIAN Yan. An analysis of associated factors of thyroid hormones of prematurity[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(4): 78-79,3
Authors:ZHU Yan-ke  CHEN Si-hu  WANG Qiu  CHI Mei-zhu  QIAN Yan
Affiliation:ZHU Yan-ke1,CHEN Si-hu2,WANG Qiu1,CHI Mei-zhu1,QIAN Yan1(1The Neonatal Intensive Care Unit of the First Affiliated Hospital of Wenzhou Medical College,Zhejiang Wenzhou 325000,China,2The Second Affiliated Hospital of Wenzhou Medical College,China)
Abstract:
Objectives:To investigate the factors that affected the serum levels of triiodothyronine,thyroxine and thyroid stimulating hormone of prematurity.Methods:Serum triiodothyronine(T3),thyronine(T4) and thyrotropin(TSH) in 353 preterm infants were detected on the fourteenth day after birth and 14 factors which may be associated were collected.Multiple linear regression was used to analyze the factors that affected serum thyroid hormones.Results:Among the 14 factors,T3 levels at d14 were positively associated wi...
Keywords:Prematurity  Thyroid function  Gestation  Birthweight  Transient hypothyroidism  
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