应用ABCD2评分评估短暂性脑缺血发作预后

目的 评估短暂性脑缺血发作(TIA)发病7 d内动脉粥样硬化性血栓性事件(AT).方法 应用ABCD2评分回顾性研究符合本研究人选标准的198例TIA临床资料,根据评分分为低危组(≤3分)和中-高危组(≥4分),分别统计TIA发病7 d内AT事件的发生率、种类及危险因素,并在两组间进行卡方检验.结果 既往病史依次为高血压病、糖尿病、冠心病、脑梗死和高脂血症,低危组TIA发病7 d内AT事件发生率为6.19%(6/97例),均为TIA复发;中.高危组为14.85%(15/101例),其中TIA复发2例、缺血性卒中10例、TIA复发+缺血性卒中1例、心绞痛1例、心肌梗死1例,两组均无周围性血管病以及血管病性死亡;中-高危组TIA后7 d内AT事件明显多于低危组(51.70%比27.27%,P<0.05).结论 ABCD2评分≥4分的TIA病人在发病后7 d内有更高的发生AT事件的风险.

The application of ABED2 Score in evaluation of the prognosis in transient ischemic attack

Objective To assess the incidence, types and risk factors of atherothrombotic events (AT) within 7 days after transient ischemic attack (TIA) with ABCD2 Score in Chinese patients. Methods With ABCD2 Score, we retrospectively reviewed the medical records of 198 TIA patients ,which met the inclusion criteria of our study. They were divided into a low risk group (ABCD2 ≤3) and a moderate-high risk group(ABCD2≥4) and the incidence, types and risk factors of AT within 7 days after TIA were evaluated and compared respectively with χ2 test between the two groups. Statistic significance was considered as P < 0.05. Results The order of the frequency of accompanying diseases was hypertension 68.18% (135/198), diabetes 23.74% (47/198), coronary artery disease 21.72% (43/198), ischemic stroke 15.66% (31/198) and hyperlipemia 12. 63% (25/198). AT within 7 days after TIA was observed in 6.19% (6/97) of the patients in the low risk group, all of them were suffering from TIA recurrence. In the moderate-high risk group, 14. 85% (15/101) of the patients experienced AT, including 2 eases of TIA recurrence, 10 cases of ischemic stroke, 1 case of both TIA recurrence and ischemic stroke, 1 case of angina pectoris and 1 case of myocardial infarction. There was no peripheral vascular disease or death from vascular disease. Incidence of AT within 7 days in the moderate-high risk group was significantly higher than that in the low risk group (51.70% vs 27. 27%, P < 0.05). Conclusion TIA patients with ABCD2 ≥4 are at higher risk of AT within 7 days after TIA onset.