Lymphocyte subpopulations in patients with acne vulgaris

T- and B-lymphocyte subpopulations were measured in the peripheral blood of patients with varying severity of acne and in acne-free control subjects. Increased severity of acne correlated with an increased number of T lymphocytes, helper T cells and B cells, while the number of suppressor T cells remained normal and did not alter significantly. This evidence suggests that there is no lack of regulation of the immune response in acne patients.