血清降钙素原和C反应蛋白联合检测在儿童急性肺炎诊断中的应用价值

目的：分析血清降钙素原和C反应蛋白联合检测在儿童急性肺炎诊断中的应用价值。方法随机选取2013年1月-2014年12月该院收治的150例儿童急性肺炎患者作为观察组，同期进行体检的80例健康儿童作为对照组，两组均采用电化学发光法和免疫散射比浊法检测血清中降钙素原和C反应蛋白水平。结果观察组细菌性肺炎患者和支原体性肺炎患者血清降钙素原和C反应蛋白水平与对照组患者比较，差异有统计学意义(P<0.05﹚。细菌性肺炎和支原体肺炎恢复期血清降钙素原和C反应蛋白水平明显下降，与急性期相比差异有统计学意义(P<0.05﹚。结论血清降钙素原联合C反应蛋白水平检测在诊断儿童急性肺炎中有一定应用价值，可作为肺炎诊断及鉴别肺炎类型的参考指标。

Application Value of Combined Detection of Serum Procalcitonin and C-re-active Protein in the Diagnosis of Children with Acute Pneumonia

Objective To analyze the application value of combined detection of serum procalcitonin and C-reactive protein in the diagnosis of children with acute pneumonia. Methods 150 cases of children with acute pneumonia treated in our hos-pital from January 2013 to December 2014 were selected as the observation group, 80 cases of healthy people receiving physical examination in our hospital at the same period were selected as the control group, the serum procalcitonin and C-reactive protein level of the two groups were detected according to the electrochemiluminescence and Immune scatter tur-bidity. Results The serum procalcitonin and C-reactive protein level in the patients with bacterial pneumonia and patient with mycoplasmal pneumonia in the observation group were obviously different from those in the control group (P<0.05﹚, the serum procalcitonin and C-reactive protein level in bacterial pneumonia and mycoplasmal pneumonia were obviously decreased in the recovery phase compared with those in the acute phase, and the difference was statistically significant (P<0.05﹚. Conclusion The combined detection of serum procalcitonin and C-reactive protein level has a certain application value in the diagnosis of children with acute pneumonia, which can be used as the reference indexes for the diagnosis and differentiation of pneumonia.