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Expression of human herpesvirus 8 in primary pulmonary hypertension |
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| Authors: | Cool Carlyne D Rai Pradeep R Yeager Michael E Hernandez-Saavedra Daniel Serls Amanda E Bull Todd M Geraci Mark W Brown Kevin K Routes John M Tuder Rubin M Voelkel Norbert F |
| Affiliation: | Pulmonary Hypertension Center, University of Colorado Health Sciences Center, Denver 80262, USA. |
| Abstract: | Severe pulmonary hypertension constitutes a group of diseases characterized by complex, lumen-occluding vascular lesions that develop in genetically susceptible persons. The only viral infection associated with severe pulmonary hypertension has been that due to human immunodeficiency virus type 1, but neither the viral genome nor viral antigens have been demonstrated in pathologic lesions. |
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