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| Fractalkine和CX3CR1━新发现的一对与白细胞趋化和粘附功能密切相关的分子 | |
| 引用本文： | 金亮,王百忍,鞠躬. Fractalkine和CX3CR1━新发现的一对与白细胞趋化和粘附功能密切相关的分子[J]. 中国病理生理杂志, 2000, 0(12) |
| 作者姓名： | 金亮 王百忍 鞠躬 |
| 作者单位： | 第四军医大学全军神经科学研究所!陕西西安710032 |
| 摘 要： | 趋化因子超家族由许多成员组成 ,以往根据趋化因子结构域中的保守半胱氨酸的数目和位置将其分为ＣＸＣ (α)、ＣＣ ( β)和Ｃ (γ) 3型 ,最近又有学者[1 ] 发现了一种新的趋化因子 ,其趋化因子结构域具有ＣＸ3Ｃ基序 ,因此被称为第四型或δ型趋化因子。其首位成员被称为ｆｒａｃｔａｌｋｉｎｅ。Ｆｒａｃｔａｌｋｉｎｅ分子是Ｂａｚａｎ等[1 ] 经Ｂｌａｓｔ分析法从美国国家生物技术信息中心 (ｎａｔｉｏｎａｌｃｅｎｔｅｒｆｏｒｂｉｏｔｅｃｈｎｏｌｏｇｙｉｎｆｏｒｍａｔｉｏｎ ,ＮＣＢＩ)的表达序列标签 (ｅｘ ｐｒｅｓｓｅｄｓｅｑｕ… |
| 关 键 词： | 趋化性 白细胞 细胞粘着分子 |
Fractalkine and CX3CR1 have intimate relationships with chemotaxis and adhesion of leukocyte |
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| JIN Liang,WANG Bai-ren,JU Gong. Fractalkine and CX3CR1 have intimate relationships with chemotaxis and adhesion of leukocyte[J]. Chinese Journal of Pathophysiology, 2000, 0(12) | |
| Authors: | JIN Liang WANG Bai-ren JU Gong |
| Abstract: | Fractalkine has been recognized as the first member of the fourth chemokine family recently and its receptor, CX3CR1, was identified afterwards. This pair of ligand/receptor play important roles in the migration and adhesion of peripheral leukocyte through different ways. They are also likely to be related to the embryogenesis and regeneration of several organs and may possess some functions in the central nervous system. |
| Keywords: | Chemotaxis leukocyte Cell adhesion molecules |
| 本文献已被 CNKI 等数据库收录！ | |