| 杠板归缓释栓剂的制备及体外释放度研究 |
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| 引用本文： | 李莉,何谨,黄家宇,敖芳芳,许超飞. 杠板归缓释栓剂的制备及体外释放度研究[J]. 贵阳医学院学报, 2013, 38(4): 369-371 |
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| 作者姓名： | 李莉 何谨 黄家宇 敖芳芳 许超飞 |
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| 作者单位： | 1. 贵阳医学院药学院,贵州贵阳,550004
2. 贵阳医学院附院药剂科,贵州贵阳,550004 |
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| 摘 要： | 目的:制备杠板归缓释栓剂并研究其体外释放度。方法:以甘油明胶为栓剂基质,用乳化法制备杠板归缓释微球,将微球加入栓剂基质中制成缓释栓剂,并检测其体外释放度。结果:完成杠板归缓释栓剂的制备,体外释放度试验表明,制得的杠板归缓释栓剂体外缓释效果明显,释药行为符合一级动力学方程。结论:杠板归缓释栓剂处方简单,缓释效果明显,可用于工业化大生产。
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| 关 键 词： | 杠板归 栓剂 释放度 |
Preparation and In vitro Release of Polygonum perfoliatum Sustained-Release Suppositories |
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| LI Li , HE Jin , HUANG Jiayu , AO Fangfang , XU Chaofei. Preparation and In vitro Release of Polygonum perfoliatum Sustained-Release Suppositories[J]. Journal of Guiyang Medical College, 2013, 38(4): 369-371 |
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| Authors: | LI Li HE Jin HUANG Jiayu AO Fangfang XU Chaofei |
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| Affiliation: | LI Li;HE Jin;HUANG Jiayu;AO Fangfang;XU Chaofei;School of Pharmacology,Guiyang Medical College;Section of Pharmaceutical Preparation,the Affiliated Hospital of Guiyang Medical College; |
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| Abstract: | |
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| Keywords: | Polygonum perfoliatum L. suppositories release rate |
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