Warm vs. cold perfusion techniques to rescue rodent liver grafts |
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Authors: | Andrea Schlegel Philipp KronRolf Graf Philipp Dutkowski Pierre-Alain Clavien |
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Affiliation: | Department of Surgery, University Hospital Zurich, Swiss HPB and Transplant Center, Zurich, Switzerland |
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Abstract: | |
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Keywords: | DCD, donation after cardiac death HOPE, hypothermic oxygenated perfusion UW solution, University of Wisconsin solution HMGB-1, high mobility group box-1 protein 8-OHdG, 8-hydroxy-2-deoxy guanosine H& E, haematoxylin and eosin ROS, reactive oxygen species DAMPs, damage associated molecular pattern signalling CD68, macrosialin ELISA, enzyme-linked immunosorbent assay SECs, sinusoidal endothelial cells WI, warm ischemia IPRL, isolated perfused rat liver TLR-4, Toll-like receptor 4 MPO, myeloperoxidase IL-6, interleukin 6 IL-10, interleukin 10 IL-1β, interleukin 1β TNF-α, tumor necrosis factor alpha ICAM-1, intercellular adhesion molecule-1 NSE, neuron specific enolase CXCL-5 (ENA-78), epithelial neutrophil-activating protein 78 |
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