寻常痤疮细菌感染病因学探讨

对１３２例寻常痤疮患者的皮损内容取材，同时进行需氧菌和厌氧菌培养。其中有１１２例分离到细菌，细菌培养阳性率８４．８％。１１２例共分离出１３７株细菌，其中需氧菌７５株，厌氧菌６２株，痤疮丙酸杆菌的分离率为４２．３％。１１２例中５８例分离到痤疮丙酸杆菌，阳性率为５１．８％；２４例为混合感染。１６例用特丽仙溶液治疗６周后，细菌培养阴转率为７５．０％；脓疱、丘疹、粉刺数的平均值分别由２．０６、１７．６９和２３．６３个减至０．７５、３．６３和１５．５６个。结果证明细菌感染在寻常痤疮病因学中的作用。

A study on the etiology of infecting bacteria about acne vulgaris

The samples were collected from 132 cases of acne vulgaris. The materials were then cultured in both anaerobic and aerobic conditions. The results showed that rates of positive cultures were 84. 8% (112/132). 137 strains of bacteria existed in 112 cases of patients, among which 75 were earobic and 62 anaerobic. The positive isolation rates of propionibacterium acnes (P. acne) were 42. 3%. 58 of the 112case were P. acne, and the positive rates of P. acne were 51.8%. The other 24 cases were mixed infections . After Talacin T topical solution treatment for 6 weeks in 16 patients, the rates of converted negative cultures were 75.0%; the averages values of pustules, papules and comedones decreased from 2. 06, 17.69 and 23. 63 to 0. 75, 3. 63 and 15. 56 respectively. The results indicate that becteria infection is associated with etiology of acne vulgaris.