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艾迪注射液对胃癌患者术后细胞免疫功能的影响
引用本文:胡廷辉,李瑾,许志平. 艾迪注射液对胃癌患者术后细胞免疫功能的影响[J]. 中国全科医学, 2009, 12(3)
作者姓名:胡廷辉  李瑾  许志平
作者单位:福建中医学院附属宁德市医院肿瘤科,福建省宁德市,352100
摘    要:目的 探讨艾迪注射液对胃癌患者术后细胞免疫功能的影响.方法将40例行胃癌根治术的患者随机分为A、B两组,各20例,另选择40例健康体检者为对照组.B组患者仅给予常规抗炎支持治疗,A组患者术后在常规治疗基础上给予艾迪注射液静脉滴注.比较胃癌组和对照组术前细胞免疫功能[用外周血T细胞亚群(CD3+、CD4+、CD8+T细胞及CD4+/CD8+)变化判断细胞免疫功能]及A、B组患者术前与术后14 d的细胞免疫功能.结果 (1)胃癌患者术前CD3+、CD4+、CD8+T细胞所占百分比及CD4+/C8+值与对照组比较,差异均有统计学意义(P<0.01).(2)B组患者术后CD3+、CD4+、CD8+T细胞所占百分比及CD4+/CD8+值与术前比较,差异均无统计学意义(P>0.05).(3)A、B两组患者术后CD3+、CD4+、CD8+T细胞所占百分比及CD4+/CD8+值间差异有统计学意义(P<0.01).结论胃癌患者细胞免疫功能处于抑制状态,手术不能逆转胃癌患者的免疫抑制状态,而术后应用艾迪注射液可逆转胃癌患者的免疫抑制状态.

关 键 词:胃肿瘤  艾迪注射液  免疫  细胞

Effect of Aidi Injection on Cellular Immunity in Postoperative Patients with Gastric Cancer
HU Ting-hui,LI Jin,XU Zhi-ping. Effect of Aidi Injection on Cellular Immunity in Postoperative Patients with Gastric Cancer[J]. Chinese General Practice, 2009, 12(3)
Authors:HU Ting-hui  LI Jin  XU Zhi-ping
Affiliation:HU Ting-hui,LI Jin,XU Zhi-ping.Department of Tumor,Ningde Municipal Hospital,Ningde 352100,China
Abstract:Objective To investigate the effect of Aidi injection on cellular immune function in postoperative patients with gastric cancer.Methods Totally 40 gastric cancer patients receiving radical operation were randomly divided as A and B groups,with 20 in each;and 40 healthy physical examinees were enrolled as the controls.After operation,the patients in B group received only conventional anti-inflammatory treatment,and those in A group received additional Aidi injection.The immune functions(Changes of CD3+,CD4+,...
Keywords:Stomach nioplasms  Aidi injection  Immunity  cellular  
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