降钙素原检测用于肝硬化自发性腹膜炎的价值

目的观察肝硬化自发性腹膜炎（SBP）患者血清降钙素原（PCT）水平,及治疗中的变化情况,探讨PCT对于SBP患者早期诊断及预后判断的价值。方法选取该院80例肝硬化腹水患者,按有无自发性腹膜炎分为两组,其中30例患者并发自发性腹膜炎,50例无自发性腹膜炎（非SBP）,动态观察患者体温、腹部体征、腹水检查、血常规、PCT,了解PCT变化与SBP的关系。结果 SBP组PCT水平明显高于非SBP组,PCT水平与SBP预后正相关,P〈0.05。结论在肝硬化腹水患者中,PCT对合并自发性腹膜炎有较高的诊断价值,PCT值高低与病情呈正相关,早期检测PCT对及早使用抗生素,改善预后有意义。

The Significance of Procalcitonin Detection in Liver Cirrhosis with Sponta- neous Bacterial Peritonitis

Objective To observe the level of procalcitonin （PCT）of liver cirrhosis patients with spontaneous bacterial peritonitis （SBP） and its changes in treatment so as to study the value of PCT in early diagnosis and prognostic judgement for the patients . Methods 80 liver cirrhosis patients with ascites in our department were divided into two groups, SBP group （n=30） and non-SBP group （n=50）, according to whether they had spontaneous bacterial peritonitis. The temperature, abdominal signs, ascites, routine blood test and PCT of the groups were observed dynamically so as to study the relationship between the changes of PCT and SBP. Results The PCT level of SBP group was obviously higher than that of non-SBP group. PCT level was positively related to the prognosis of SBP （P〈0.05）. Conclusion The PCT level has diagnostic value for patients with liver cirrhosis and ascites. The PCT level is positively correlated with the severity of the disease. Early PCT detection and early use of antibiotics can improve the prognosis of the patients.