C反应蛋白与冠心病的相关性研究

目的：探讨C反应蛋白（CRP）与冠心病发生、发展的关系及其对预后的预测价值。方法：采用免疫透射比浊法测定136例入选对象CRP的含量。其中冠心病106例，包括稳定型心绞痛（SAP）组38例。不稳定型心绞痛（USAP）组39例、急性心肌梗死（AMI）组29例；正常对照组30例。结果：（1）冠心病患中CRP异常升高率为67．9％；（2）SAP组CRP有所升高，但无统计学意义；USAP和AMI组较正常对照组CRP明显升高（P均＜0．01）；（3）AMI的CRP水平较USAP组更高（P＜0．05）。结论：CRP升高是冠心病发生、发展的危险因素之一，它与冠心病严重程度呈正相关，对预后有一定的预测价值。

Study of correlation between C-reactive protein and coronary heart disease

Objective:Toe explore the correlation between C|reactive protein(CRP) and coronary heart disease(CHD) and its prognostic value.Methods:The plasma CRP levels of 136 patients were determined by immune transmission turbidity method.In which 38 cases were stable angina pectoris(SAP),39 cases were unstable angina pectoris(USAP),29 cases were myocardial infarction(AMI),30 cases were normal controls.Results:(1)CRP positive rate was 67 9% in CHD patients;(2)CRP positive level increased in SAP group,but not significant difference when compared with control group;(3) The CRP positive levels of SAP and AMI group significantly increased( P <0 01) when compared with control group,but its level of AMI group more increased( P <0 05).Conclusion:The CRP positive level increase is a risk factor of CHD.Its level is positive correlation with severity extent of CHD,and it is a valuable index on predicting prognosis.