| 后程加速超分割三维适形放疗食管癌的临床研究 |
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| 引用本文： | 蔡凯,胡联民,陈刚,刘俊波,黄常江. 后程加速超分割三维适形放疗食管癌的临床研究[J]. 实用肿瘤杂志, 2011, 26(6): 631-634 |
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| 作者姓名： | 蔡凯 胡联民 陈刚 刘俊波 黄常江 |
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| 作者单位： | 广西贵港市中医医院肿瘤科,广西贵港,537100 |
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| 基金项目： | 广西贵港市科学研究与技术开发计划项目(贵科产0504002) |
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| 摘 要： | 目的 探讨食管癌后程加速超分割三维适形放疗的疗效及其预后相关因素.方法 回顾分析后程加速超分割三维适形放疗67例食管癌患者的临床资料,分析生存率、不良反应、死亡原因及预后影响因素.结果 中位随访时间16月.1、2、3、4年生存率分别为67.6％、50.9％、45.8％和35.9％,中位生存期为28月.Ⅰ～Ⅲ期食管癌1、2、3、4年生存率分别为76.9％、63.6％、57.3％,44.9％.单因素分析结果显示肿瘤部位、肿瘤长度、TNM分期对生存率有影响.Cox回归模型多因素分析结果表明肿瘤部位、肿瘤长度、TNM分期是独立预后因素,而性别、年龄与预后无关.死亡原因主要是局部未控或复发、淋巴结转移以及远处转移.结论 后程加速超分割三维适形放疗食管癌患者的局部控制率和生存率较常规治疗的历史水平明显提高,肿瘤部位、肿瘤长度、TNM分期是影响预后的独立因素.
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| 关 键 词： | 食管肿瘤/放射疗法 放射疗法/方法 存活率 预后 回顾性研究 |
Late-course accelerated hyperfractionated three-dimensional conformal radiotherapy for esophageal carcinoma |
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| CAI Kai,HU Lian-min,CHEN Gang,et al. Late-course accelerated hyperfractionated three-dimensional conformal radiotherapy for esophageal carcinoma[J]. Journal of Practical Oncology, 2011, 26(6): 631-634 |
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| Authors: | CAI Kai HU Lian-min CHEN Gang et al |
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| Affiliation: | CAI Kai,HU Lian-min,CHEN Gang,et al(Department of Radiation Oncology,Zongyi′s Hospital of Guigang,Guigang,537100,China) |
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| Abstract: | Objective To investigate the curative effect and prognostic factors of late course accelerated hyperfractionated three-dimensional conformal radiotherapy(LCAH-3DCRT) in patients with esophageal carcinoma.Methods The clinical data of 67 cases of esophageal carcinoma treated by LCAH-3DCRT were analyzed retrospectively.The clinical data included survival rate,adverse reaction,causes of death and prognostic factors.Results The median time of follow-up was 16 months.The 1-,2-,3-,and 4-year survival rates were 67... |
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| Keywords: | esophageal neoplasms/radiotherapy radiotherapy/methods survival rate prognosis retrospective stuides |
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