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局麻下电视胸腔镜手术诊治恶性胸腔积液的探讨
引用本文:李简,王晓新,宋言峥,贺钢枫,张诗杰,黄斌,陈鸿义. 局麻下电视胸腔镜手术诊治恶性胸腔积液的探讨[J]. 癌症, 2001, 20(6): 654-656
作者姓名:李简  王晓新  宋言峥  贺钢枫  张诗杰  黄斌  陈鸿义
作者单位:北京大学第一医院胸外科,;北京大学第一医院胸外科,;北京大学第一医院胸外科,;北京大学第一医院胸外科,;北京大学第一医院胸外科,;北京大学第一医院胸外科,;北京大学第一医院胸外科,
摘    要:目的:探讨局麻下电视胸腔镜手术(video-thoracoscopic surgery,VTS)诊治恶性胸腔积液的安全性和效果。方法:自2000年1月到2001年1月,探索性地在局麻下对8例恶性胸腔积液患者和7例疑患恶性胸腔积液者实施了VTS。其中3例为无法耐受全麻的高危患者。结果:对8例恶性胸腔积液患者分别进行了VTS-肺纤维膜剥脱、滑石粉洒胸膜固定术(2例)和VTS-滑石粉喷洒胸膜固定术(6例)。对7例疑患恶性胸腔积液者首先进行了VTS-胸膜腔探查,发现积液由胸膜病变引起者5例,胸膜活检均诊为转移腺癌,随后进行了VTS-滑石粉喷洒胸膜固定术;另2例脏壁层胸膜均正常,证实积液为纵隔淋巴结广泛肿大造成胸膜淋巴液引流障碍所致。以上操作在局麻下顺利完成。手术时间30-120min。期间病人的心率、血压及血氧饱和度均无明显变化。术后无严重并发症和死亡。术后住院时间7-10天。随访1-8个月,平均5个月,胸腔积液均得到控制,未见复发。与控制积液有关的花费平均为3000元。结论:局麻下进行VTS诊治恶性胸腔积液是安全、有效的。该方法经济、创伤少,值得推广应用。

关 键 词:胸腔积液/治疗  胸腔镜/治疗应用  疗效  安全性
文章编号:1000-467X(2001)06-0654-03
修稿时间:2001-01-07

Video-Thoracoscopic Surgery under Local Anesthesia for Management of Malignant Pleural Effusion
LI Jian,WANG Xiao-xin,SONG Yan-zhen,HE Gang-feng,ZHANG Shi-jie,HUANG Bing,CHEN hong-yi. Video-Thoracoscopic Surgery under Local Anesthesia for Management of Malignant Pleural Effusion[J]. Chinese journal of cancer, 2001, 20(6): 654-656
Authors:LI Jian  WANG Xiao-xin  SONG Yan-zhen  HE Gang-feng  ZHANG Shi-jie  HUANG Bing  CHEN hong-yi
Abstract:Objective: Malignant pleural effusion is a common symptom and often presents a challenge for diagnosis and treatment. When video-thoracoscopic surgery (VTS) was introduced, it was quickly adapted to manage pleural effusions by thoracic surgeons. To date, general anesthesia with single-lung ventilation is usually considered a necessity during VTS approaches. Method: From January 2000 to January 2001, patients with known (n = 8) or suspected (n = 7) malignant pleural effusion were operated through VTS under local anesthesia. ReSults: In the patients with malignant pleural effusion, after the pleural fluid was evacuated, VTS-removal of enveloping fibrous membrane of lung (n = 2) and VTS-talc insufflations (n = 8) were performed. In the patients with suspected malignant pleural effusion, after diagnostic VTS procedures (exploration and pleural biopsies for the pleural lesions), malignancy was confirmed in all patients. In which 5 due to pleural metastatic carcinoma and another two due to impaired pleural lymphatic drainage from mediastinal lymph nodes tumor. Then, VTS-talc insufflations were performed for the former 5 patients. The above procedures were all finished under local anesthesia within 30 - 120 minutes. Hemodynamics were maintained well during the operation. The duration of the postoperative chest drainage was 1 - 8 days (mean = 4 days). There was neither severe postoperative complications nor mortality. Talc pleuracentesis was successful in all cases in controlling recurrence of effusion after a mean follow-up of 5 months. The average medical fee for controlling pleural effusion was 3000 RMB. Conclusions: Video-thoracoscopic operations can be performed safely under local anesthesia for diagnosis and treatment of pleural effusion. The novel approaches can lower the cost for management pleural effusion with satisfactory results.
Keywords:Pleural effusion  Thoracoscopic surgery
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