| 珍视明滴眼液中硼砂、硼酸及总硼的含量测定 |
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| 引用本文： | 周平,张倩,赵翠,王伯涛.珍视明滴眼液中硼砂、硼酸及总硼的含量测定[J].中国实验方剂学杂志,2011,17(19):61-63. |
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| 作者姓名： | 周平 张倩 赵翠 王伯涛 |
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| 作者单位： | 南京工业大学药学院,南京,211816 |
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| 基金项目： | "十一五"国家科技支撑计划重点项目(2008BAI55B00) |
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| 摘 要： | 目的:建立珍视明滴眼液中硼砂、硼酸及总硼的含量测定方法。方法:结合微量滴定法与常量滴定法测定珍视明滴眼液中硼砂、硼酸及总硼的含量。结果:硼砂的线性范围为8～16 mg,线性方程Y=504.52X-0.14(r=0.998 8),加样回收率为98.29%(n=6,RSD 1.37%)。硼酸的线性范围为50～70 mg,线性方程Y=141.74X+0.07,(r=0.999 7),加样回收率为97.02%(n=6,RSD 0.78%)。总硼的线性范围在0.8～1.2 mmol,线性方程Y=9.51X-0.05(r=0.999 7),加样回收率为95.29%(n=6,RSD 0.75%)。结论:该方法简单、准确度高、易于推广,可用于珍视明滴眼液的质量评价。
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| 关 键 词： | 珍视明滴眼液 硼砂 硼酸 总硼 |
| 收稿时间： | 2011/1/14 0:00:00 |
Quantitative Analysis of Borax, Boric Acid and Total Boron in Zhengshiming Diyanye |
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| ZHOU Ping,ZHANG Qian,ZHAO Cui and WANG Bo-tao.Quantitative Analysis of Borax, Boric Acid and Total Boron in Zhengshiming Diyanye[J].China Journal of Experimental Traditional Medical Formulae,2011,17(19):61-63. |
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| Authors: | ZHOU Ping ZHANG Qian ZHAO Cui and WANG Bo-tao |
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| Institution: | School of Pharmaceutical Science, Nanjing University of Technology, Nanjing 211816, China;School of Pharmaceutical Science, Nanjing University of Technology, Nanjing 211816, China;School of Pharmaceutical Science, Nanjing University of Technology, Nanjing 211816, China;School of Pharmaceutical Science, Nanjing University of Technology, Nanjing 211816, China |
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| Abstract: | Objective: To establish the quantitative analysis method for borax, boric acid and total boron in Zhengshiming diyanye. Method: Borax, boric acid and total boron in Zhengshiming Diyanye were determined by micro-titration and constant titration. Result: The linear range of borax was from 8-16 mg, and the regression equation was Y=504.52X-0.14( r=0.998 8) with the average recovery rate 98.29%(n=6,RSD 1.37%). The linear range of boric acid was from 50-70 mg, and the regression equation was Y=141.74X+0.07, r=0.999 7 with the average recovery rate 97.02%(n=6,RSD 0.78%). The linear range of total boron was from 0.8-1.2 mmol, and the regression equation was Y=9.51X-0.05, r=0.999 7 with the average recovery rate 95.29%(n=6,RSD 0.75%). Conclusion: This method is simple with high accuracy and easy to popularize, can provide foundation for the quality control of Zhengshiming diyanye. |
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| Keywords: | Zhengshiming diyanye borax boric acid total boron |
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