| 乙肝清缓释片质量标准 |
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| 引用本文： | 王兴,张卫国,李莹,李晓倩,王萍,雷磊. 乙肝清缓释片质量标准[J]. 中国实验方剂学杂志, 2011, 17(15): 105-107 |
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| 作者姓名： | 王兴 张卫国 李莹 李晓倩 王萍 雷磊 |
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| 作者单位： | 西南交通大学生命科学与工程学院,成都,610031 |
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| 基金项目： | 中央高校基本科研业务会专项资金(SWJTU09ZT29) |
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| 摘 要： | ![]()
目的:建立乙肝清缓释片的质量标准。方法:采用薄层色谱法(TLC)对制剂中的贯叶连翘进行鉴别;采用高效液相色谱法(HPLC)测定制剂中的金丝桃素含量,Phenomenence Luna C18色谱柱(4.6 mm×250 mm,5μm),流动相乙腈-0.025mol.L-1 KH2 PO4水溶液(85∶15),检测波长588 nm。并对制剂进行释放度考察。结果:TLC图谱分离度好,检出斑点清晰;金丝桃素在0.076～0.76μg呈良好的线性关系,r=0.999 9,平均回收率98.66%,RSD 2.51%。结论:该法操作简便、可行,重复性好,可作为乙肝清缓释片的质量控制标准。
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| 关 键 词： | 乙肝清缓释片 质量标准 薄层色谱法 金丝桃素 高效液相色谱法 |
| 收稿时间： | 2011-04-03 |
Quality Standard of Yiganqing Sustained-released Tablet |
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| WANG Xing,ZHANG Wei-guo,LI Ying,LI Xiao-qian,WANG Ping and LEI Lei. Quality Standard of Yiganqing Sustained-released Tablet[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(15): 105-107 |
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| Authors: | WANG Xing ZHANG Wei-guo LI Ying LI Xiao-qian WANG Ping LEI Lei |
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| Affiliation: | School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China;School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China;School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China;School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China;School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China;School of Life Science and Engineering, Southwest JiaoTong University, Chengdu 610031, China |
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| Abstract: | ![]()
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| Keywords: | Yiganqing Sustained-released-table quality standard TLC hypericin HPLC |
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