广东省江门市首例人感染H7N9禽流感病例的流行病学调查

目的为了及时有效地控制人感染H7N9禽流感疫情,防制疫情扩散蔓延。方法采用流行病学调查方法,调查病例的发病经过、可能的感染来源、传播途径及暴露因素等,医学观察患者的密切接触者。结果确诊l例人感染H7N9禽流感病例,经抢救无效死亡。患者有明确的活禽市场接触史,咽拭子检测H7N9禽流感病毒核酸阳性。患者的密切接触者无继发病例。通过强化监测流感病例215例,均未发现H7N9禽流感病毒核酸阳性。患者暴露的活禽交易市场外环境20份标本检出3份H7N9禽流感病毒核酸阳性。结论以后仍有可能出现人感染H7N9禽流感病例,各项防控措施必须加强。

Epidemiological investigation on the first case of human infection with H7N9 avian influenza in Jiangmen Guangdong province

Objective To control the spread of human infection with H7N9 avian influenza, and prevent the outbreak.Methods Epidemiological survey was carried out including the clinical course, possible infection source, transmission route and risk factors, etc. Strict observation was made on close contacts of the patient. Meanwhile the patient underwent clinical diagnosis, treatment and laboratory tests. Results The patient was confirmed to be infected with highly pathogenic human avian influenza H7N9 virus as ascertained by experts of Health and Family Planning Commission of Guangdong, and died after failed in rescue.The patient had confirmed with exposure to poultry market, showing positive result in the H7N9 nucleic acid detection of the swab. Close contacts of the patient had no secondary cases.By expanding surveillance on 215 cases of influenza-like illness（ILI）, no H7N9 positive cases was found. However, on live poultry market that the patient exposure to,three external environment specimens were detected to be H7N9 positive. Conclusion The human infection with H7N9 avian influenza could be appeared later. Further studies and works are needed for prevention and control of human infection with H7N9 avian influenza.