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育子丸治疗精核蛋白异常男性不育30例临床分析
引用本文:王旭初,李海松,潘天明. 育子丸治疗精核蛋白异常男性不育30例临床分析[J]. 中华男科学杂志, 2006, 12(11): 1044-1046
作者姓名:王旭初  李海松  潘天明
作者单位:1. 沧州中西医结合医院生殖医学中心,河北,沧州,061001
2. 北京中医药大学附属东直门医院,男科中心,北京,100700
3. 北京大学第三医院生殖中心,北京,100083
摘    要:
目的:研究育子丸临床治疗精核蛋白异常男性不育的方法及效果。方法:观察30例男性不育患者用育子丸治疗前后精核蛋白、精液参数、性激素的变化情况。结果:育子丸治疗1个疗程(3个月)后,治愈9例,显效15例,无效6例。治疗后,组蛋白/精核蛋白的比例[(0.72±0.32)]较治疗前[(1.34±0.52)]下降,差异有显著性(P<0.01);精液质量较治疗前明显改善(P<0.05);LH、T水平较治疗前显著提高(P<0.01)。治疗后中医症候改善25例。结论:育子丸治疗精核蛋白异常的男性不育具有良好疗效。

关 键 词:男性不育  育子丸  精核蛋白  精子
文章编号:1009-3591(2006)11-1044-03
收稿时间:2006-04-26
修稿时间:2006-08-18

Clinical Analysis of Yuziwan in the Treatment of 30 Sterile Men with Abnormal Protamine
WANG Xu-chu,LI Hai-song,PAN Tian-ming. Clinical Analysis of Yuziwan in the Treatment of 30 Sterile Men with Abnormal Protamine[J]. National journal of andrology, 2006, 12(11): 1044-1046
Authors:WANG Xu-chu  LI Hai-song  PAN Tian-ming
Affiliation:Center of Reproductive Medicine, Cangzhou Hospital of Integrated TMC and Western Medicine, Cangzhou, Hebei 061001, China. yixiangzhai@sina.com
Abstract:
OBJECTIVE: To study the clinical application and effects of Yuziwan in the treatment of male sterility patient with abnormal protamine. METHODS: The changes of protamine, semen and sex hormones of 30 male sterility patients treated by Yuziwan were observed before and after the treatment. RESULTS: After a 3-month course of treatment, 9 cases were cured, 15 obviously improved and 6 failed to respond. The ratio of histone to protamine was decreased from (1.34 +/- 0.52) before the treatment to (0.72 +/- 0.32) after it, with significant difference (P < 0.01), the semen quality obviously improved (P < 0.05), and the LH and T levels markedly raised (P < 0.01). Yuziwan evidently improved the abnormal protamine, sperm quality and endocrine function of the sterility patients. CONCLUSION: Yuziwan has good curative effect on male sterility.
Keywords:male infertility  Yuziwan  protamine  sperm
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