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| ~（99m）Tc标记卵巢癌单抗的实验研究 | |
| 引用本文： | 林文玉,钱和年,冯捷,李文锦,许宏, 高伯山,齐桂英,秦淑玲,梁铁军,聂玉新. ~（99m）Tc标记卵巢癌单抗的实验研究[J]. 北京大学学报(医学版), 1995, 0(6) |
| 作者姓名： | 林文玉 钱和年 冯捷 李文锦 许宏 高伯山 齐桂英 秦淑玲 梁铁军 聂玉新 |
| 作者单位： | 北京医科大学人民医院妇科肿瘤研究室，北京医科大学人民医院核医学科 |
| 摘 要： | 用９９ｍＴｃ标记卵巢癌单抗，对标记方法、纯化手段、还原后抗体存放时间与标记率关系、标记物免疫活性以及用该标记物对荷瘤裸鼠放免显象进行探讨，提示９９ｍＴｃ标记卵巢癌单抗的可行性。 |
| 关 键 词： | 99m锝硫胶，抗体，单克隆，卵巢肿瘤 |
EXPERIMENTAL RESEARCH OF99mTc LABELLING OVARIAN CARCINOMA MONOCLONAL ANTIBODY |
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| Abstract: | 9mTc is more advantageous than other radio isotopes because of its short half-life,suitable energy,and small dosage of radiation absorption for patients.We have labelled ovarian carcinoma monoclonal antibody with 99mTc,and studied the labelling method,purifying method,the relation between the storage time of reduced antibody and the labelling rate,the immuno-activity of labeled agents,and the immunoimaging of nude mice bearing human o-varian serous adenocarcinoma.It showed the feasibility of labelling OC McAb with 99mTc. |
| Keywords: | Headings Technetium TC 99m sulfur colloid Antihodies monoclonal Ovarian neoplasms |
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