SELDI-TOF-MS在结直肠癌血清蛋白质组学中的应用 |
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引用本文: | 吴星烨,傅仲学. SELDI-TOF-MS在结直肠癌血清蛋白质组学中的应用[J]. 国际肿瘤学杂志, 2009, 36(1). DOI: 10.3760/cma.j.issn.1673-422X.2009.01.018 |
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作者姓名: | 吴星烨 傅仲学 |
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作者单位: | 重庆医科大学附属第一医院普通外科,400016;重庆医科大学附属第一医院普通外科,400016 |
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摘 要: | 蛋白质组学为结直肠癌的许多研究领域开拓了新的视野,表面增强激光解析电离飞行时间质谱(SELDI-TOF-MS)技术推动了其在结直肠癌血清蛋白质组学研究中的应用.在针对结直肠癌早期诊断、判断分期、监测治疗效果等方面进行了积极的探索.随着这一技术的成熟,它对结直肠癌的诊断、治疗具有广阔的应用前景.
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关 键 词: | 结直肠肿瘤 蛋白质组学 血清 |
SELDI-TOF-MS in serum proteomics of colorectal carcinoma |
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Abstract: | Proteomics opens new visions in many research fields of colorectai cancer.The surface en-hanced laser desorption ionization- time of flight- mass spectroscopy ( SELDI- TOF- MS) promotes its application in serum proteomics.Many positive pilot tests are done aiming at the early diagnosis, staging, monitoring re-sponse to treatment and etc.of colorectal cancer.As SELDI-TOF-MS is mature to use, it has a expansive per-spective on the clinical diagnosis and treatment of colorectal cancer. |
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Keywords: | Colorectal neoplasms Proteomics Serum |
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