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Significant Increases in Serum CA125 and CA19-9 Following Torsion from an Adenofibroma of the Ovary: A Case Report |
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| Authors: | Fujiwara Keiichi; Moriya Takuya; Mikami Yoshiki; Hiratsuka Junichi; Sawada Satoshi; Imajo Yoshinari; Kohno Ichiro |
| Institution: | 1 Department of Obstetrics and Gynecology, Kawasaki Medical School Kurashiki 2 Department of Pathology, Kawasaki Medical School Kurashiki 3 Department of Radiology, Kawasaki Medical School Kurashiki |
| Abstract: | Significant increases in the serum levels of cancer antigen125 (CA 125) and carbohydrate antigen 19-9 (CA19-9) were observedover one month prior to the removal of an ovarian adenofibroma.The serum levels of CA125 and CA19-9 decreased rapidly aftersurgery. The surface of the tumor at surgery showed marked inflammation,probably induced by the necrosis produced by torsion. Pathologically,most of the tumor was necrotic, and histo immunochemical stainingof the viable cells was weak for CA125 but intense for CA19-9.Clinicopathological observations of the case suggested thatCA125 and CA19-9 might be stimulated in the cells by inflammationor that originally existing CAT25 and CA19-9 were released fromthe tumor cells following the cell necrosis. |
| Keywords: | CA 125 CA19-9 Torsion of ovarian tumor Benign ovarian tumor Adenofibroma Peritoneal inflammation |
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