孕期女性膀胱功能障碍研究

目的:初步探讨孕期女性膀胱功能障碍变化。方法:按照世界尿控协会推荐的尿动力学检查标准方法对65例孕期女性志愿者(孕妇组)进行尿动力学检查。14例上尿路疾病而下尿路功能正常的已婚未育妇女做对照组。结果:测定功能性膀胱容量和正常尿意膀胱压测定容量均显著低于对照组;孕妇组最大尿道压、最大尿道闭合压和功能尿道长度均显著高于对照组;但孕妇组AG值和尿道阻力因子均无一存在膀胱出口梗阻。膀胱压力容积/压力流率测定其余相关指标两组均无统计学意义。孕妇组排尿后收缩发生率显著高于对照组。结论:孕期女性多表现为膀胱感觉敏感,尿道控尿能力增高,但膀胱排空能力未受到明显影响。

To investigate the changes of bladder function in pregnant women

Objective:To investigate the changes of bladder function in the pregnant women.Methods:Free uroflowmotry, eystometry, prossuro-flow-electromyography and static urethral pressure profile measurements according to the recommendations of the International Continence Society (ICS) were performed on 65 women before labor who were all volunteers. 14 women with upper urinary tract diseases but having normal lower urinary tract function were taken as a control group who were married but not born.Results:Functional bladder volume (FBV) and normal desire cystometric capacity (NDCC) of pregnant women were respectively lower than those of control group. The Pure. max, Pure.closure.max and urethral functional length of pregnant women in static urethral pressure profile were respectively higher than those of control group. However, Abrams-Griffiths number (AG) and urethral resistance factor (URA) of pregnant women showed that no one locate in obstructed area, and the significant differences in AG and URA between pregnant women and control group were no found. There were no significant differences in Qmax,max cystometric capacity(MCC),bladder compliance(BC), Pdet before voiding ,Pdet at Qmax and Pdet.max among two groups. There was contraction after voiding in twenty-nine pregnant women and it was significantly higher than that of control group.Detrusor instability were found in eight pregnant women.Conclusion:It is suggested that bladders of women in the pregnant women are sensitive and static urethral pressure parameters increased, but the ability of emptying bladder is still normal.