血清降钙素原与C反应蛋白对感染性疾病的诊断价值

目的：探讨血清降钙素原（PCT）与c反应蛋白（CRP）对感染性疾病的诊断价值。方法：回顾性分析我院2012年1月至2012年8月间102例确诊为感染性疾病的患者的临床资料，探讨164例患者血清降钙素原及C反应蛋白的水平及其与感染性疾病之间的联系。以上病例均经我院实验室病原学检查及血清学检查等临床实验确诊。结果：血清降钙素原和C反应蛋白与感染的严重程度相关，感染源及疾病程度不同时，血清降钙素原及C反应蛋白水平不同。细菌性感染组与正常对照组的降钙素原相比差异有统计学意义（P〈O．05）；细菌感染组与病毒感染组降钙素原相比较时，差异有统计学意义（P〈0．05）；病毒感染组与正常对照组降钙索原比较无统计学差异（P〉0．05）。三组之间的C反应蛋白相比，均有统计学差异（P〈0．05）。结论：利用血清降钙素原和C反应蛋白的检测对临床感染进行诊断，可以提高感染性疾病诊断的准确率，且可根据实验结果判断感染性疾病的严重程度，值得临床推广。

Using the Procalcitonin and C-reactive Protein in the Diagnosis of Infectious Diseases

Objective： To investigate the serum procalcitonin （PCT） and C-reactive protein （CRP） in the diagnosis of infectious diseases. Method： A retrospective analysis was designed to explore the relation- ship of procalcitonin and C-reactive protein levels and infectious disease. All the cases were confirmed by clinical trials of pathogenic examination in our hospital clinical laboratory. Result： The level of procalcitonin and C-reactive protein in serum is related to the severity of the infection disease. The concentration of pro- calcitonin between bacterial infection group and normal control group was different statistically significant （P 〈0.05） ; the concentration of procalcitonin in the bacterial infection group compared to the original with the viral infection group, the difference was statistically significant （ P 〈0.05 ） ; the concentration of procalcito- nin in the infection group and normal control group was no significant difference （ P〉 0.05 ）. C-reactive protein compared among the three groups, were statistically significant （ P 〈0.05 ）. Conclusion： Using the serum procalcitonin and C-reactive protein in the detection of clinical infection diagnosis can improve the ac- curacy of the diagnosis in the infectious diseases.