Analysis of Prognostic Factors for Patients Undergoing Renal Replacement Therapy With Acute Kidney Injury Prior to Living Donor Liver Transplantation |
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| Affiliation: | 1. Department of Surgery, Seoul St. Mary''s Hospital, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea;2. Department of Surgery, Bucheon St. Mary''s Hospital, College of Medicine, Catholic University of Korea, Bucheon, Republic of Korea;1. Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan;2. Department of Medicine, Emory University, Atlanta, Georgia;1. Department of Urology and Transplant Surgery, Toda Chuo General Hospital, Saitama, Japan;2. Department of Urology, Tokyo Women''s Medical University, Tokyo, Japan;3. Department of Urology, Tokyo Women''s Medical University, Yachiyo Medical Center, Chiba, Japan;4. Department of Urology, Juntendo University Urayasu Hospital, Chiba, Japan;1. Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea;2. Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Korea;1. Department of Urology, Yamagata University Faculty of Medicine, Yamagata, Japan;2. Department of Cardiology, Pulmonology, and Nephrology, Yamagata University Faculty of Medicine, Yamagata, Japan |
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| Abstract: | ![]()
BackgroundAcute kidney injury (AKI) is a common complication in patients undergoing liver transplantation (LT) for end-stage liver disease (ESLD), and renal replacement therapy (RRT) is required in many cases. This study was performed to identify the prognostic factors for patients undergoing RRT owing to AKI before living donor liver transplantation (LDLT).Materials and MethodsFrom January 2010 to December 2018, LDLT was performed in 464 adult patients in our center. We reviewed 33 patients who underwent RRT before LDLT among 464 consecutive cases. Patients who continued to RRT after LDLT or who underwent subsequent kidney transplantation were considered to have not recovered from renal impairment.ResultsAmong 33 patients, there were 23 patients in the recovery group and 10 patients in the nonrecovery group. The preoperative duration of RRT was shorter in the recovery group, but it was not statistically significant. In the nonrecovery group, diabetes mellitus was found to have a higher prevalence and ischemic time was longer. Other perioperative factors were not significantly different between the 2 groups. After LDLT, the peak total bilirubin level was higher, and the intensive care unit stay was longer in the nonrecovery group. The overall survival rate was higher in the recovery group.ConclusionsLiver transplant recipients who maintain RRT after LDLT have poor outcome. It is necessary to know the risk factors and manage them well, perioperatively. |
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