Neuromyelitis optica spectrum disorders and systemic lupus erythematosus: A case series from a university center |
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| Affiliation: | 1. EA 481 Laboratoire de Neurosciences Intégratives et Cliniques, Université de Franche-Comté, UBFC, Besançon, France;2. CIC-1431 Inserm Département de Neurologie, CHU Besançon, Besançon, France;3. Télémédecine 360, TLM360, Paris, France;4. RUN-FC, Besançon, France;5. Département de neurologie, CHU Besançon, Besançon, France;1. Department of Internal Medicine, Hedi Chaker Hospital, University of Sfax, 3029 Sfax, Tunisia;2. Department of Neurology, Hospital Of Gabes, University of Sfax, 3029 Sfax, Tunisia;3. Department of Radiology, Hedi Chaker Hospital, University of Sfax, 3029 Sfax, Tunisia;1. Department of Neurology, Henry Ford Health System, Detroit, MI, USA;2. Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA |
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| Abstract: | ![]()
Neuromyelitis optica spectrum disorders (NMOSD) are immune-mediated inflammatory diseases of the central nervous system (CNS), which preferentially affect the optic nerves and the spinal cord. Anti-aquaporin 4 antibody is a specific serological marker. Systemic lupus erythematosus (SLE) is a rheumatologic disease that may affect the CNS. There are several reports about the coexistence of NMOSD and autoimmune diseases, mainly those of rheumatologic origin. We describe three different cases in which SLE and NMOSD subsequently occurred, drawing attention to the clinical heterogeneity, the challenge and the importance of recognizing this possible association. |
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| Keywords: | Neuromyelitis optica spectrum disorders Systemic lupus erythematosus Autoimmune diseases |
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