长期持续性非卧床腹膜透析患者增加透析剂量对营养及充分性的影响

目的 前瞻性观察增加透析剂量对长期持续性非卧床腹膜透析(CAPD)患者的营养及透析充分性的影响。方法 36例CAPD患者，均常规行8升／日腹膜透析，其中13例夜间留腹2升，增加腹膜透析剂量为10升／日，随访三个月，评价其营养及透析充分性。结果 13例增加透析剂量组TKt/w和TCcr均显著升高(P＜0．05)，净超滤亦增加(P＜0．05)，血浆白蛋白水平虽有下降，但未达到统计学意义。结论 增加腹膜透析剂量能显著提高TKt/v和TCcr，使透析更为充分，且增加超滤量，对腹膜透析患者的长期存活有意义，且对其营养状态短期内无影响。

The impact of increasing dialysis volume on nutritional status and peritoneal dialysis adequacy of continuous ambulatory peritoneal dialysis patients

Objective To study the effect of increasing dialysis volume on nutritional status and peritoneal dialysis adequacy of continuous ambulatory peritoneal dialysis patients. Methods Thirty - six CAPD patients who took conventional 8 - L dialysafe perday were investigated, in which 13 patients had one additional 2 - L exchange during the night (10 - L group) . Dialysis adequcy parameters (TKt/v, TCcr) , net ultrafiltration (nUF) and nutritional status (serum albumin) were measured at 0 and 3 months. Results There were significant increases in TKt/v, TCcr and nUF in 10 - L group after 3 months ( P < 0.05). The serum albumin level were slightly decreased ( P > 0.05). Conclusion Increasing dialysis volume may effectively increase TKt/v, TCcr and nUF in CAPD patients, but may not affect nutritional status during short period.