Severity of acute hepatitis and its outcome in patients with dengue fever in a tertiary care hospital Karachi,Pakistan (South Asia) |
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| Authors: | Om Parkash Aysha Almas SM Wasim Jafri Saeed Hamid Jaweed Akhtar Hasnain Alishah |
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| Affiliation: | (1) Section of Gastroenterology, Department of Medicine, Aga Khan University Hospital Karachi, Pakistan;(2) Section of Internal Medicine, Department of Medicine, Aga Khan University Hospital Karachi, Pakistan |
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| Abstract: | Background Liver injury due to dengue viral infection is not uncommon. Acute liver injury is a severe complicating factor in dengue, predisposing to life-threatening hemorrhage, Disseminated Intravascular Coagulation (DIC) and encephalopathy. Therefore we sought to determine the frequency of hepatitis in dengue infection and to compare the outcome (length of stay, in hospital mortality, complications) between patients of Dengue who have mild/moderate (ALT 23-300 IU/L) v/s severe acute hepatitis (ALT > 300 IU/L). |
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