黑老虎的化学成分研究

目的研究冷饭团Kadsura coccinea根茎(黑老虎)的化学成分。方法运用硅胶柱色谱、制备薄层、RP-HPLC等方法分离纯化,根据理化性质以及光谱数据,对得到的化合物进行结构鉴定。结果共分离得到9个化合物,分别鉴定为南五味子素O(1)、kadsuracoccinic acid A(2)、kadsuralignan F(3)、新南五味子木脂宁(4)、南五味子素N(5)、kadsureneA methyl ester(6)、原儿茶酸(7)、丁香酸(8)、胡萝卜苷(9)。结论化合物1为新化合物,命名为南五味子素O;化合物8为首次从该植物中分离得到。

Chemical constituents in roots and vine stems of Kadsura coccinea

Objective To study the chemical constituents from the roots and vine stems of Kadsura coccinea.Methods The compounds were isolated and purified by column chromatography,preparative TLC,and RP-HPLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Nine compounds were separated and identified as kadsulignan O(1),kadsuracoccinic acid A(2),kadsuralignan F(3),neokadsuranin(4),kadsulignan N(5),kadsurene A methyl ester(6),protocatechuic acid(7),syringic acid(8),and daucosterol(9).Conclusion Compound 1 is a new compound named kadsulignan O.Compound 8 is firstly isolated from roots and vine stems of K.coccinea.