腰腹联合手法治疗腰椎间盘突出症的生化指标分析

目的：观察腰腹部联合手法治疗腰椎间盘突出症的生化指标。方法：将75例患者随机分为3组,每组25例：对照组采用常规输液和卧床休息治疗;治疗1组采用传统手法治疗配合常规输液和卧床休息治疗;治疗2组采用腰腹部联合手法配合常规输液和卧床休息治疗。3组患者分别于治疗前与治疗结束后进行血浆血栓素B2（TXB2）、6-酮-前列腺素F1α（6-K-PGF1α）、白细胞介素-1β（IL-1β）、肿瘤坏死因子-α（TNF-α）的测定。结果：3组治疗后TXB2、IL-1β、TNF-α含量均明显降低,6-K-PGF1α含量治疗后较治疗前明显升高。对照组与治疗1组比较差异无统计学意义（P〉0.05）;治疗2组与对照组、治疗组比较差异有统计学意义（P〈0.05）。结论：本研究中腰腹联合手法治疗后生化指标有明显改善。说明腰腹联合手法可加速血液循环,促进机体新陈代谢,有利于神经根水肿的消退。这可能是其效果优良的作用机制之一。

Biochemical Analysis of Combined Lumbo-abdominal Manipulation in the Treatment of Lumbar Intervertebral Disc Herniation

Abstract Objective：To observe the biochemical result of combined lumbo-abdominal manipulation in the treatment of lum- bar intervertebral disc herniation. Methods：75 patients were randomly divided into 3 groups. 25 patients underwent conven- tional medication and bed rest therapies in control group. 25 patients underwent traditional manipulation combined conven- tional medication and bed rest therapies in treatment group 1; 25 patients underwent combined lumbo-abdominal manipula- tion and conventional medication and bed rest therapies in treatment group 2. TXB2, IL-1β ,TNF-α and 6-K-PGFlo were taken before and after treatment to assess the therapeutic effects. Results：TXB2, IL-1β, TNF-α levels were reduced evi- dently in all three groups and 6-K-PGF-α level increased evidently after treatment. There was no difference between the con- trol group and the treatment group 1 （P〉0.05）. There was significant difference between the control group and the treatment group 2（P0.05）. Conclusion：Improved biochemical indicator shows that combined lumbo-abdominal manual therapy can accelerate the blood circulation of patients, promote metabolism and relieve the edema of nerve root. Perhaps it is one of the main mechanisms.