信号核素134Cs诱发体细胞和生殖细胞畸变效应比较研究

对１３４Ｃｓ诱发体细胞和生殖细胞的畸变效应进行了比较研究。方法观察内污染不同放射性活度１３４Ｃｓ时诱发同体骨髓细胞和精原细胞染色体畸变的量效关系，以及同一放射性活度１３４Ｃｓ作用不同时间诱发上述两种细胞的染色体畸变产额。结果研究发现，１３４Ｃｓ内照射诱发的骨髓细胞染色体畸变产额显著高于精原细胞，而其诱发的染色体畸变类型均以染色单体型畸变为主。结论由不同放射性活度１３４Ｃｓ所诱发的染色体畸变产额而言，骨髓细胞要比精原细胞高出１．５～５倍。

Comparison of chromosome aberration yields induced by signal radionuclide 134Cs in somatic and germ cells

bjective To compare the aberration inducing effect of ¹³⁴Cs in somatic and germ cells. Method Studying dose response relationship for ¹³⁴Cs at different radioactivities inducing chromosome aberrations in somatic and germ cells,as well as ¹³⁴Cs in the same radioactivity inducing aberration yields after different time intervals. Results It was demonstrated that the chromosome aberration yields induced by ¹³⁴Cs in bone marrow cells were significantly higher than those in spermatogonia.Most of chromosome aberrations in bone marrow cells and spermatogonia were similar in chromatid type. Conclusion The results suggest that the dose-response relationship of aberration yields in bone marrow cells induced by ¹³⁴Cs at different radioactivities is 1.5-5 times higher than that in spermatogonia.