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| RADIOFREQUENCY ABLATION USING HYPERTONIC SALINE SOLUTION INSTILLATION： AN EX VIVO STUDY | |
| 引用本文： | 陈磊 胡兵 朱玲. RADIOFREQUENCY ABLATION USING HYPERTONIC SALINE SOLUTION INSTILLATION： AN EX VIVO STUDY[J]. 上海第二医科大学学报, 2007, 19(2): 147-150 |
| 作者姓名： | 陈磊 胡兵 朱玲 |
| 作者单位： | Department of Ultrasound, the Sixth People＇s Hospital, Shanghai Jiaotong University, Shanghai 200233, China |
| 摘 要： | Objective To determine whether radiofrequency ablation using hypertonic saline solution instillation can increase the extent of thermally mediated coagulation in ex vivo pig liver tissue. Methods Fifty-six radiofrequency ablation lesions were produced in fresh ex vivo pig＇s liver. According to different saline solutions, the lesions were divided into six groups： 25% acetic acid, 18% NaCl, 10% NaCl, 5% NaCl, 0.9% NaCl, and distilled water. After radiofrequency ablation, the lesions size and morphology were measured and compared.Results Using different instillation, the volume of coagulation necrosis was different： 25% acetic acid 〉18% NaCl 〉10% NaCl 〉5% NaCl 〉0.9% NaCl〉distilled water. Conclusion Radiofrequency ablation using hypertonic saline solution instillation can increase the volume of radiofrequency ablation induced necrosis. |
| 关 键 词： | 高渗盐溶液 射频消融术 外周血巨核祖细胞体外扩增研究 医学实验 |
RADIOFREQUENCY ABLATION USING HYPERTONIC SALINE SOLUTION INSTILLATION: AN EX VIVO STUDY |
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| CHEN Lei,HU Bing,ZHU Ling. RADIOFREQUENCY ABLATION USING HYPERTONIC SALINE SOLUTION INSTILLATION: AN EX VIVO STUDY[J]. Journal of Shanghai Second Medical University(Foreign Language Edition), 2007, 19(2): 147-150 | |
| Authors: | CHEN Lei HU Bing ZHU Ling |
| Abstract: | Objective To determine whether radiofrequency ablation using hypertonic saline solution instillation can increase the extent of thermally mediated coagulation in ex vivo pig liver tissue. Methods Fifty-six radiofrequency ablation lesions were produced in fresh ex vivo pig's liver. According to different saline solutions, the lesions were divided into six groups: 25% acetic acid, 18% NaCl, 10% NaCl, 5% NaCl, 0.9% NaCl, and distilled water. After radiofrequency ablation, the lesions size and morphology were measured and compared.Results Using different instillation, the volume of coagulation necrosis was different: 25% acetic acid >18% NaCl >10% NaCl >5% NaCl >0.9% NaCl>distilled water. Conclusion Radiofrequency ablation using hypertonic saline solution instillation can increase the volume of radiofrequency ablation induced necrosis. |
| Keywords: | radiofrequency ablation hypertonic saline solution ex vivo study |
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