膝骨关节炎中医辨证分型与中医体质类型关联性分析

目的:调查膝骨关节炎人群中医体质类型及中医证型分布情况,初探膝骨关节炎中医证型与中医体质的关联性。方法:收集188例膝骨关节炎患者为观察组,100例非膝骨关节炎为对照组,逐一判定中医体质类型及中医证型,统计中医体质及中医证型的分布情况,并采用Logistic回归分析,探讨膝骨关节炎与中医体质类型、中医证型与中医体质类型的关联性。结果:①观察组偏颇质以阳虚质、气虚质、阴虚质最常见;②阳虚质、气虚质、阴虚质为膝骨关节炎正向风险因素;③观察组症候表现复杂,以肝肾亏虚证为主,其次为寒湿痹阻证、气血虚弱证、气滞血瘀证;④中医证型与中医体质类型相关联,其中寒湿痹阻证与气虚质显著相关;肝肾亏虚证与阳虚质、气虚质、阴虚质显著相关;气血虚弱证与阳虚质、气虚质、阴虚质显著相关;气滞血瘀证与阳虚质显著相关。结论:阳虚质、气虚质、阴虚质人群易患膝骨关节炎;膝骨关节炎人群以肝肾亏虚证居多,寒湿痹阻证次之,气血虚弱证和气滞血瘀证较少;从不同体质与中医证型的关系来看,寒湿痹阻证与气虚质显著相关;肝肾亏虚证与阳虚质、气虚质、阴虚质显著相关;气血虚弱证与阳虚质、气虚质、阴虚质显著相关;气滞血瘀证与阳虚质显著相关。

Association between TCM Syndromes and TCM Constitutions of Knee Osteoarthritis

Objective To investigate the distribution of TCM Syndromes and TCM constitutions in knee osteoarthritis population,and to further explore the relationship between TCM Syndromes and TCM constitutions of knee Osteoarthritis.Methods 188 cases of knee osteoarthritis were collected as observation group and 100 cases of non-knee osteoarthritis as control group.The TCM Syndromes and TCM constitutions were determined one by one,and the distribution of TCM Syndromes and TCM constitutions was counted.Logistic regression analysis was used to explore the relationship between knee osteoarthritis and TCM constitutions,as well as TCM Syndromes and TCM constitutions.Results①Constitutions of yang asthenia,qi asthenia,and yin asthenia were the most common TCM constitutions in the observation group,②Constitutions of yang asthenia,qi asthenia,and yin asthenia were the positive risk factors of knee osteoarthritis.③In the observation group,the liver and kidney deficiency syndrome was the most common TCM syndrome,followed by cold-dampness obstruction syndrome,deficiency of both qi and blood syndrome,stagnation of qi and blood stasis syndrome.④Cold-dampness obstruction syndrome was significantly correlated with constitutions of qi asthenia.The liver and kidney deficiency syndrome was significantly associated with constitutions of yang asthenia,qi asthenia,and yin asthenia.What s more,deficiency of both qi and blood syndrome was significantly correlated with constitutions of yang asthenia,qi asthenia,and yin asthenia.In addition,stagnation of qi and blood stasis syndrome was significantly correlated with constitutions of yang asthenia.Conclusion Patients with constitutions of yang asthenia,qi asthenia,and yin asthenia are prone to knee osteoarthritis,and the the liver and kidney deficiency syndrome was the most common TCM syndrome followed by cold-dampness obstruction syndrome,deficiency of both qi and blood syndrome,stagnation of qi and blood stasis syndrome.Cold-dampness obstruction syndrome was significantly correlated with constitutions of qi asthenia.The liver and kidney deficiency syndrome was significantly associated with constitutions of yang asthenia,qi asthenia,and yin asthenia.What s more,deficiency of both qi and blood syndrome was significantly correlated with constitutions of yang asthenia,qi asthenia,and yin asthenia.In addition,stagnation of qi and blood stasis syndrome was significantly correlated with constitutions of yang asthenia.