| 养血饮颗粒中黄芪甲苷的含量测定 |
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| 引用本文： | 李军鸽,李苹,陈志国,柳洪峰,唐秋竹. 养血饮颗粒中黄芪甲苷的含量测定[J]. 中国民族民间医药杂志, 2020, 0(7): 27-30 |
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| 作者姓名： | 李军鸽 李苹 陈志国 柳洪峰 唐秋竹 |
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| 作者单位： | 长春中医药大学;吉林敖东集团力源制药股份有限公司 |
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| 基金项目： | 养血饮颗粒质量标准研究。 |
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| 摘 要： | 目的:建立高效液相色谱法测定养血饮颗粒中黄芪甲苷的含量,提高养血饮颗粒质量标准,为养血饮颗粒制剂评价研究奠定基础。方法:采用Agilent 1260高效液相色谱仪,Agilent蒸发光检测器(低温型);以乙腈-水(38∶62)为流动相;检测波长为270 nm;空气发生器为0.4 MPa;漂移管温度为50℃对黄芪甲苷进行含量测定。结果:黄芪甲苷在0.66~6.63μg范围内线性关系良好,回收率为97.81%(RSD=3.94%,n=9),精密度、稳定性、重现性均符合要求。结论:该方法可以用于养血饮颗粒中黄芪甲苷的含量测定。
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| 关 键 词： | 养血饮颗粒 黄芪甲苷 含量测定 蒸发光检测器 质量标准 |
Determination on Contents of Astragaloside Glycoside in Yangxueyin Keli |
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| LI Junge,LI Ping,CHEN Zhiguo,LIU Hongfeng,TANG Qiuzhu. Determination on Contents of Astragaloside Glycoside in Yangxueyin Keli[J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2020, 0(7): 27-30 |
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| Authors: | LI Junge LI Ping CHEN Zhiguo LIU Hongfeng TANG Qiuzhu |
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| Affiliation: | (Changchun University of Traditional Chinese Medicine,Changchun 130117,China;Jilin Aodong Group Liyuan Pharmaceutical incorporated company,Dunhua 133700,China) |
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| Abstract: | Objective A high performance liquid chromatography(HPLC)method was established for the determination of astragaloside glycoside in Yangxueyin Keli,and the quality standard of Yangxueyin granules was improved.Methods Adopt Agilent 1260 high performance liquid chromatography,Agilent evaporative light detector(low temperature type);use acetonitrile-water(38∶62)as mobile phase;detection wavelength is 270 nm;air generator is 0.4 MPa;drift tube temperature is 50℃,determination of astragaloside glycoside.Results Astragaloside glycoside has a good linear relationship in the range of 0.66 to 6.63μg,and the recovery rate is97.81%(RSD=3.94%,n=9).The precision,stability,and reproducibility meet the requirements.Conclusion The method can be used for the determination of astragaloside glycoside in Yangxueyin Keli. |
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| Keywords: | Yangxueyin Keli Astragaloside Glycoside Content Determination Evaporative Light detector Quality Standard |
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