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氯化铯诱发在体心脏触发性心律失常的实验研究
引用本文:杨向军,惠杰,汪康平,蒋文平.氯化铯诱发在体心脏触发性心律失常的实验研究[J].中国心脏起搏与心电生理杂志,1993(1).
作者姓名:杨向军  惠杰  汪康平  蒋文平
作者单位:苏州医学院附属第一医院心血管研究室,苏州医学院附属第一医院心血管研究室,苏州医学院附属第一医院心血管研究室,苏州医学院附属第一医院心血管研究室 苏州 215006,苏州 215006,苏州 215006,苏州 215006
摘    要:心内膜单相动作电位研究表明,单相动作电位的复极进程能够正确反映心肌细胞动作电位复极时程。狗静脉注射氯化铯后早期后除极电位(EAD)的发生率为100%,单相动作电位90%复极时程明显延长(224.4±50.6ms VS 368.4±34ms),与QT间期延长相一致。氯化铯诱发的室性心律失常发生于EAD顶峰,触发心律联律间期与EAD联律间期密切相关。硫酸镁使EAD和室性心律失常同时消失。提示该心律失常为EAD触发活性所致。

关 键 词:单相动作电位  早期后除极电位  心律失常  氯化铯  硫酸镁

The Study of the Triggered Activities Induced by Cesium Chloride in Vivo
Yang Xiangjun,Hui Jie,Wang Kangping,et al.The Study of the Triggered Activities Induced by Cesium Chloride in Vivo[J].Chinese Journal of Cardiac Pacing and Electrophysiology,1993(1).
Authors:Yang Xiangjun  Hui Jie  Wang Kangping  
Abstract:The study of the monophasic action potential(MAP) from endocardium demonstrated that the duration of MAP might faithfully represented that of the transmembrane action potential. MAPD_(90) and QT interval were markedly prolonged simultaneously. Early afterdepolarization(EAD)were closely related to arrhythmias;(l)the potentials of the ventricular arrhythmias were on the peak of EAD;(2)the conpling interval of the afterdepolarization and the ventricular arrhythmias were nearly interrelated(r =0. 97);(3)EAD and the arrhythmias were suppressioned by magnesium simultaneously.
Keywords:Monophasic action potential  Early afterdepolarization  Arrhythmias  Cesium choiride  Magnesium sulfate  
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