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| 盐酸司他斯汀片治疗常年性变应性鼻炎的疗效分析 | |
| 引用本文： | 刘燕,潘发明,胡士高,蒋淑飞. 盐酸司他斯汀片治疗常年性变应性鼻炎的疗效分析[J]. 安徽医药, 2010, 14(5): 581-582. DOI: 10.3969/j.issn.1009-6469.2010.05.041 |
| 作者姓名： | 刘燕 潘发明 胡士高 蒋淑飞 |
| 作者单位： | 安徽医科大学公共卫生学院,安徽,合肥,230032;安徽省药物研究所,安徽,合肥,230022;安徽医科大学公共卫生学院,安徽,合肥,230032;安徽省药品审评认证中心,安徽,合肥,230022;回音必集团浙江亚东制药有限公司,浙江,诸暨,311800 |
| 摘 要： | 目的观察盐酸司他斯汀片对常年性变应性鼻炎的临床疗效。方法随机双盲双模拟平行对照临床试验,实际纳入试验组19例,对照组20例。试验组（盐酸司他斯汀,1.0 mg）及对照组（富马酸氯马斯汀片,1.0 mg）,两组均每天服药2次、模拟片1片,均连服14 d。在服药第7天、第14天观察治疗前后两组的疗效。结果两组均能有效控制和改善病情,试验组与对照组的总有效率均为65%,两组间差异无显著性。结论盐酸司他斯汀片治疗常年性变应性鼻炎临床疗效确切,与富马酸氯马斯汀疗效相当。 |
| 关 键 词： | 盐酸司他斯汀 常年性变应性鼻炎 临床疗效分析 |
Efficacy of setastine hydrochloride tablets in perennial allergic rhinitis patients |
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| LIU-Yan,PAN Fa-ming,HU Shi-gao,JIANG Shu-fei. Efficacy of setastine hydrochloride tablets in perennial allergic rhinitis patients[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(5): 581-582. DOI: 10.3969/j.issn.1009-6469.2010.05.041 | |
| Authors: | LIU-Yan PAN Fa-ming HU Shi-gao JIANG Shu-fei |
| Affiliation: | LIU-Yan1,2,PAN Fa-ming2,HU Shi-gao3,JIANG Shu-fei4(1.Department of Epidemiology and Biostatistics,School of Public Health,Anhui Medical University,Hefei 230032; 2.Institute of Materia Medica of Anhui,Hefei 230022;3.Anhui Center For Drug Evaluation & Certification,Hefei 230022; 4.Zhejiang Yadong Pharmaceutical Co.Ltd,Zhuji 311800) |
| Abstract: | Aim To evaluate the efficacy of setastine hydrochloride tablets in treatment of perennial allergic rhinitis patients.Methods A randomized double-blind and parallel-controled clinical trial was conducted.Nineteen patients in trial group received 1.0 mg setastine hydrochloride and one simulation tablet twice daily and twenty in control group received 1.0 mg clemastine fumarate and one simulation tablet twice daily in fact for continuous 14 days.Then,the state of illness was evaluated and the clinical effects were compared between pretreatment and posttreatment,1 week and 2 weeks after treatment.Results Both setastine hydrochloride and clemastine fumarate can improve the symptoms of perennial allergic rhinitis.The total effective rate was 65%.There was no significant difference between the two groups.Conclusion Similar to clemastine fumarate,setastine hydrochloride is effective for treatment of perennial allergic rhinitis. |
| Keywords: | setastine hydrochloride tablet perennial allergic rhinitis curative effect |
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