胰腺癌CT导引近距离放疗穿刺入路选择技术与策略

目的探讨胰腺癌125I永久性插植放疗前术前胃肠准备结合多入路穿刺技术进行粒子布源的可行性和应用价值。方法回顾分析136例（男91例,女45例）胰腺癌患者经CT导向下125I粒子插植放疗,患者平均年龄为61.6岁（48～82岁）。其中胰头癌53例,胰颈癌21例,胰体癌35例,胰尾癌13例,全胰腺癌24例。平均3.74cm（2.85cm～6.5cm）;33例肝内单发转移,16例多发转移,67例腹腔干周围淋巴结肿大。所有患者均存在不同程度的持续性腰背部或腹部疼痛。所有患者均存在不同程度的持续性腰背部或腹部疼痛。125I植入前39例行胆肠吻合,17例行支架或引流减黄;25例行外放疗,33例行静脉或动脉化疗。61例治疗前、后肝转移行动脉化疗。所有患者均行术前胃肠道准备,并采用多入路结合125I粒子植入。患者术后1、2、3月行增强CT扫描,以后为每3个月一次,同时检查肿瘤标志物,术后随访9～43个月。结果本组136例病人手术均按计划顺利完成,术前胃肠道准备有效率为76.5%（91/103）。无一例术中及术后出现胰漏、胆漏、出血、脏器穿孔及感染等主要并发症。术后一年内疼痛缓解率87.5%（119/136）,局部有效率83....

CT-guided Iodine-125 brachytherapy for pancreatic cancer:feasibility and utility of pretreatment gastrointestinal preparation combined multiaccess implantation

Objective to evaluate the feasibility and utility of pretreatment gastrointestinal preparation combined multi-access needle puncture for 125I implantation in pancreatic cancer treatment.Methods Retrospectively evaluate 136 patients(male,91;female,45)(mean age,61.6;range,48-82)underwent CT-guided percutaneous 125I implantation or intraoperating implantation in pancreatic cancer treatment.There were 53 in head of pancreas,21 in neck of pancreaa,35 in body of pancreas,13 in tail of pancreas and 24 in whole pan...