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| 壮药红鱼眼三萜类成分镇痛和抗炎活性实验研究 | |
| 引用本文： | 黄彬彬,马健雄. 壮药红鱼眼三萜类成分镇痛和抗炎活性实验研究[J]. 中国药业, 2013, 0(18): 17-18 |
| 作者姓名： | 黄彬彬 马健雄 |
| 作者单位： | [1]广西壮族自治区桂林市第二人民医院药剂科,广西桂林541001 [2]广西医科大学,广西南宁530021 [3]广西金海堂药业有限责任公司新药研发中心,广西南宁530313 |
| 基金项目： | 广西壮族自治区科技厅资助课题,项目编号：09321005. |
| 摘 要： | 目的研究壮药红鱼眼三萜类成分的镇痛和抗炎活性。方法采用扭体法观察镇痛作用；用二甲苯使小鼠致炎和醋酸致小鼠腹腔毛细血管通透性增加观察抗炎作用。结果红鱼眼三萜类成分对醋酸致痛具有明显的镇痛作用，对二甲苯所致炎性水肿也有显著的抑制作用。结论红鱼眼三萜类成分具有较好的镇痛、抗炎活性。 |
| 关 键 词： | 红鱼眼 三萜 镇痛 抗炎 |
Study on Effects of Analgesic and Antiinflammatory Activity of Triterpenes in Phyllanthus Reticulatus |
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| Huang Binbin,Ma Jianxiong. Study on Effects of Analgesic and Antiinflammatory Activity of Triterpenes in Phyllanthus Reticulatus[J]. China Pharmaceuticals, 2013, 0(18): 17-18 | |
| Authors: | Huang Binbin Ma Jianxiong |
| Affiliation: | 1. Guilin Municipal Second People＇s Hospital, Guilin, Guangxi, China 541001; 2. Guangxi Medical University, Naning, Guangxi, China 530021; 3. New Drug Research and Development Center, Guangxi Jinhaitang Pharmaceutical Co. , Ltd. , Nanning, Guangxi, China 530313 ) |
| Abstract: | Objective To study the analgesic and antiinflammatory effects of triterpenes ingredients extracted from Phyllanthus reticula- tus. Methods The writhing method was adopted to observe the analgesic effect. The anti- inflammation effect was observed by using dimethylbenzene causing rat inflammation and acetic acid inducing rat abdominal capillary permeability increase. Results Triterpenes in- gredients extracted from Phyllanthus reticulatus had obvious analgesic effect on acetic acid caused pain and significant inhibiting effect on dimethylbenzene caused inflammatory edema. Conclusion The triterpenes ingredients of Phyllanthus reticulatus has better analgesic and antiinflammatory activity. |
| Keywords: | Phyllanthus reticulatus triterpenes analgesic antiinflammatory |
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