| 替比夫定治疗慢性乙型肝炎患者乙肝标志物动态联检及其意义 |
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| 引用本文： | 张静,顾国浩,甘建和,罗二平,史进方,高纯. 替比夫定治疗慢性乙型肝炎患者乙肝标志物动态联检及其意义[J]. 广东医学, 2011, 32(14): 1913-1915 |
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| 作者姓名： | 张静 顾国浩 甘建和 罗二平 史进方 高纯 |
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| 作者单位： | 苏州大学附属第一医院
苏州大学附属第一医院检验科 |
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| 基金项目： | 国家"十一五"科技重大专项子课题 |
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| 摘 要： | 目的 实验观察替比夫定治疗慢性乙型肝炎(以下简称乙肝)的疗效.方法 将83例慢性乙肝患者分成HBeAg阴性组(40例)和HBeAg阳性组(43例),均首次给予替比夫定抗病毒治疗48周,于治疗0、4、12、24、48周时联检HBV DNA、ALT水平、乙肝两对半,分析上述时间点两组患者HBV DNA转阴率、ALT复常率、...
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| 关 键 词： | 乙型肝炎病毒 慢性乙肝 HBV DNA 替比夫定 核苷类似物 |
Dynamic measurement and implication of markers of chronic hepatitis in patients treated with Telbivudine |
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| ZHANG Jing,GU Guo-hao,GAN Jian-he,LUO Er-ping,SHI Jin-fang,GAO Chun. Dynamic measurement and implication of markers of chronic hepatitis in patients treated with Telbivudine[J]. Guangdong Medical Journal, 2011, 32(14): 1913-1915 |
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| Authors: | ZHANG Jing GU Guo-hao GAN Jian-he LUO Er-ping SHI Jin-fang GAO Chun |
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| Affiliation: | ZHANG Jing,GU Guo-hao,GAN Jian-he,LUO Er-ping,SHI Jin-fang,GAO Chun.Department of Clinical Laboratory,First Affiliated Hospital,Soochow University,Suzhou 215006,China |
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| Abstract: | Objective To observe the therapeutic efficacy of telbivudine treatment on chronic hepatitis B. Methods Eighty-three patients,who were given with 48 weeks telbivudine treatment for the first time,were divided into HBeAg negative group(40 cases) and positive group(43 cases).HBV DNA,ALT level,HBV biomarkers were examined at baseline,4th,12th,24th and 48th week.HBV DNA conversion rate,ALT normalization rate,HBeAg conversion rate and seroconversion rate(HBV-M conversion ratio) were analyzed. Results In HBeAg neg... |
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| Keywords: | HBV DNA |
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