促血管生成素与胃癌血管生成的关系

目的探讨促血管生成素与胃癌微血管生成的关系，以及与胃癌微循环中存在的各种血管生长因子问的相互调控作用。方法采用文献回顾的方法，对有关促血管生成素和胃癌血管生成的关系进行综述。结果促血管生成素在胃癌微循环中的表达与胃癌的血管生成有关系，但与各种血管生成因子之间的相互调控作用仍存在争议。结论促血管生成素在胃癌微小血管的萌芽、发展、凋亡等一系列过程中扮演着重要的角色。

Relationship Between Angiopoietin and Angiogenesis of Gastric Carcinoma

Objective To study the relationship between angiopoietin and the angiogenesis of gastric carcinoma, and to investigate the inter-regulation effect between different vascular growth factors which exist in microenvironment of gastric carcinoma. Methods Literatures about angiopoietin and angiogenesis of gastric carcinoma were collected and reviewed. Results There is a relationship between the expression of angiopoietin in microcirculation and the angiogenesis of gastric carcinoma. Yet, it is still a disputable issue on the inter-regulation effect of different vascular growth factors. Conclusion Angiopoietin may play an important role in the processes of sprouting, development and apoptosis of the microvessel of gastric carcinoma.