| Abstract: | ![]()
The antifertility efficacy of both aqueous and steroidal extracts of neem ( Azadirachta indica A. Juss) leaves was studied in male Wistar rats. Intraperitoneal injections of the steroidal extract at a dose of 100 mg/kg body weight, twice a week for 10 weeks resulted in impaired spermiogenesis, increased the number of headless spermatozoa and significantly decreased ( p <0.01) motility of cauda spermatozoa, leading to a decline in the fertility index. Feeding of a 0.8% (w/v) aqueous neem leaf extract in drinking water for 7 weeks decreased serum testosterone ( p <0.01) but no effect was observed in the fertility index. © 1997 by John Wiley & Sons, Ltd. |
