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Wolff–Parkinson–White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation
Authors:Zeynep H. Coban‐Akdemir  Wu‐Lin Charng  Mahshid Azamian  Ingrid S. Paine  Jaya Punetha  Christopher M. Grochowski  Tomasz Gambin  Santiago O. Valdes  Bryan Cannon  Gladys Zapata  Patricia P. Hernandez  Shalini Jhangiani  Harsha Doddapaneni  Jianhong Hu  Fatima Boricha  Donna M. Muzny  Eric Boerwinkle  Yaping Yang  Richard A. Gibbs  Jennifer E. Posey  Xander H. T. Wehrens  John W. Belmont  Jeffrey J. Kim  Christina Y. Miyake  James R. Lupski  Seema R. Lalani
Affiliation:1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA;2. Current affiliation: Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA;3. Current affiliation: Institute of Computer Science, Warsaw University of Technology, Warsaw, Poland;4. Department of Pediatrics, Division of Cardiology, Texas Children's Hospital, Houston, Texas, USA;5. Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA;6. Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA;7. Department of Pediatrics, the University of Texas Health Science Center at Houston, Houston, Texas, USA;8. Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, USA;9. Baylor Genetics Laboratories, Baylor College of Medicine, Houston, Texas, USA;10. Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, USA;11. Cardiovascular Research Institute, Baylor College of Medicine, Houston, Texas, USA;12. Department of Pediatrics, Texas Children's Hospital, Houston, Texas, USA;13. Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA;14. Texas Children's Hospital, Houston, Texas, USA;15.

https://orcid.org/0000-0003-0707-657X;16. Seema R. Lalani, MD, Baylor College of Medicine, R806, One Baylor Plaza, BCM225, Houston, TX 77030.

Abstract:
Keywords:   ANK2  atrial fibrillation  exome sequencing  Wolff–  Parkinson–  White (WPW) syndrome
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